Conditions that affect the liver, pancreas, or biliary tract typically fall into a category known as hepato-pancreato-biliary (HPB) disease. These systems are very intricate and interconnected, with prognosis varying from manageable to critical, depending on the specific condition and its stage.

If you or a loved one has been diagnosed with an HPB condition, HPB surgery has likely been mentioned as a treatment path, and you probably have many questions and concerns.

In this article, we will discuss everything you need to know about HPB surgery, including the conditions it treats, the various types of HPB surgery, and the critical aspects to consider before choosing a surgeon to perform HPB surgery.

What is Hepato-Pancreato-Biliary Surgery?

Hepato means liver, pancreato relates to the pancreas, and the biliary system includes the gallbladder and bile ducts. Hepato-pancreato-biliary (HPB) surgery is a specialized branch of general surgery focused on treating both benign and malignant conditions affecting these systems.

HPB surgery treats many conditions, and numerous surgeries fall under the HPB surgery category. We’ll go over all of that a little further down. 

HPB surgeries are among the most challenging surgical procedures performed in general surgery. Due to their complex nature, they demand a high level of expertise and skill from surgeons. Particularly noteworthy is the necessity for an in-depth understanding of the intricate vascular networks inherent to the liver, pancreas, gallbladder, and bile ducts.

These vital organs are closely connected to a complex system of blood vessels, including veins, which play a pivotal role in sustaining their functions. As a result, a surgeon’s expertise must extend beyond basic surgical skills into the delicate realm of both HPB specialty and vascular intricacies.

Conditions That HPB Surgery Treats

Many conditions of the pancreas, liver, gallbladder, and bile ducts find resolution through Hepato-pancreato-biliary (HPB) surgery. Here are some of the most common conditions effectively addressed by HPB surgery:

Liver Tumors

Liver tumors comprise both primary liver cancers and benign tumors. Primary liver cancers may originate within the liver, while benign tumors, although non-cancerous, can still impact liver function. Colorectal cancer commonly metastasizes to the liver, as do neuroendocrine tumors originating from the gastrointestinal tract.

Liver Cancer

When it comes to liver cancer, the focus is specifically on malignant growths within the liver itself. These cancers may arise within the liver tissue and can pose significant health challenges.

Pancreas Tumors

Cancers predominantly affect the pancreatic duct, but the pancreas can also develop neuroendocrine tumors. In addition, cystic tumors present a spectrum, ranging from precancerous to malignant conditions, adding complexity to pancreatic disorders.

Pancreas Cancer

Addressing pancreatic cancer involves the comprehensive treatment of malignant growths within the pancreas. This includes tumors that originate in the pancreatic duct or neuroendocrine tumors.

Pancreatic Cysts

Pancreatic cysts, though generally non-cancerous, can present challenges. Some cysts may be precancerous, requiring careful monitoring and, in certain cases, intervention to prevent potential malignancy.

Pancreatitis

Pancreatitis is a condition characterized by inflammation of the pancreas, often unrelated to tumors or cancer. It requires specific attention to alleviate symptoms and manage underlying causes.

Gallbladder and Bile Duct Tumors

While relatively rare, cancers affecting the gallbladder and bile ducts demand specialized attention. Identified cases often require extensive general surgery to ensure effective treatment.

Gallbladder and Bile Duct Cancer

Focused on malignant growths within the gallbladder and bile ducts, this category involves the comprehensive management of cancerous conditions affecting these vital components of the digestive system.

Types of HPB Surgery 

HPB surgery serves as the primary means for potentially curing various HPB conditions, offering patients effective treatment options. Some procedures are minimally invasive, while others are invasive and complex. Each surgical procedure is distinct, addressing specific aspects of HPB conditions. 

HPB surgery can take several forms: open, robotic, and laparoscopic. Open surgeries are more invasive surgeries, such as major hepatic resection or complex gallbladder resection.


Robotic surgery is a sophisticated technique that utilizes robotic systems to perform surgical procedures with precision and control. This approach is commonly employed in HPB surgeries, offering advantages such as enhanced dexterity and minimally invasive incisions.

Laparoscopic surgery is also a minimally invasive option. This type of surgery utilizes small incisions and specialized tools with cameras to perform various surgical procedures. This technique is commonly employed in HPB surgeries, offering benefits such as reduced postoperative pain and quicker recovery.

Here are some of the most common surgeries that fall under the HPB surgery umbrella. These procedures represent a selection of the comprehensive surgical services offered at The Surgical Clinic, emphasizing our commitment to providing specialized and patient-centered care for a wide range of hepato-pancreato-biliary (HPB) conditions.

Advanced Laparoscopy

Advanced laparoscopy is a sophisticated surgical technique that employs minimally invasive approaches, using small incisions and specialized tools equipped with cameras. 

This method allows surgeons to perform intricate procedures within the abdominal cavity, including those related to hepato-pancreato-biliary (HPB) conditions. It offers benefits such as reduced postoperative pain, shorter recovery times, and minimized scarring.

Bile Duct Surgery

Bile duct surgery involves various procedures to address conditions affecting the bile ducts, including tumor removal, reconstruction, or repair.

Surgeons employ different techniques, such as open or minimally invasive approaches, to treat bile duct disorders and ensure the proper flow of bile from the liver to the small intestine.

Bile Duct Injury Repair

Bile duct injury repair is a surgical intervention aimed at correcting damage or trauma to the bile ducts.

Surgeons use specialized techniques to reconstruct or repair the affected bile ducts, ensuring optimal functioning and preventing complications associated with impaired bile flow.

Complex Bile Duct Resection

Complex bile duct resection involves the meticulous removal of specific portions of the bile duct affected by complex conditions, such as tumors or strictures.

Surgeons use advanced techniques to resect the affected segments while preserving the overall functionality of the bile duct system.

Cholangiocarcinoma Surgery 

Cholangiocarcinoma Surgery encompasses various surgical interventions tailored to address cancer originating in the bile ducts. Depending on the extent and location of the cancer, these procedures may include tumor resection, bile duct reconstruction, or liver resection.

Tumor Resection

Tumor resection involves the surgical removal of the cancerous growth, aiming to eliminate the affected tissue and prevent the spread of cholangiocarcinoma.

Bile Duct Reconstruction

This procedure focuses on rebuilding or repairing the bile ducts that may be affected by cancer. Bile duct reconstruction aims to restore the normal flow of bile and maintain the essential functions of the digestive system.

Liver Resection

Liver resection, also known as hepatectomy, is the surgical removal of a portion or the entire liver affected by cholangiocarcinoma. This complex procedure aims to eliminate the cancerous tissue while preserving the essential functions of the liver.

Cholecystectomy

Cholecystectomy is a surgical procedure focused on the removal of the gallbladder. This common procedure is often performed to address gallbladder conditions, including gallstones or inflammation, and can be conducted using laparoscopic or open techniques.

Cholecystectomy, whether laparoscopic or open, is a common surgical approach to address gallbladder conditions, including inflammation, stones, or tumors.

Gallbladder Tumor Surgery

Gallbladder tumor surgery focuses on the removal of tumors affecting the gallbladder. Surgical interventions may include gallbladder resection or other targeted procedures to address malignant or benign growths.

Gallbladder Stone Removal

Surgery for gallbladder stones involves the removal of stones from the gallbladder, often performed during cholecystectomy. Surgeons may use various techniques, including laparoscopic approaches, to address gallbladder stones and related conditions.

Duodenal Surgery

Duodenal surgery involves procedures related to the duodenum, the first part of the small intestine. Surgical interventions may include tumor resection, repair of ulcers, or treatment of other conditions affecting the duodenum.

Duodenal Tumors

Surgery for duodenal tumors entails the removal or treatment of abnormal growths in the duodenum. Depending on the nature of the tumors, surgical approaches may include resection or other targeted interventions.

Duodenal Ulcers

Surgical management of duodenal ulcers involves procedures to repair or remove ulcers affecting the duodenum. Surgeons may employ techniques such as resection or ulcer excision to address these conditions.

Gastrointestinal Cancer Surgery

Gastrointestinal cancer surgery involves the treatment of cancers affecting the gastrointestinal tract. Surgical interventions may include tumor resection, lymph node removal, or other procedures tailored to the specific type and location of the cancer.

Liver Cancer Surgery

Liver cancer surgery involves procedures to address malignant growths within the liver. Surgical interventions may include tumor resection, liver transplantation, or other targeted approaches to manage liver cancer.

Liver Tumor and Cyst Surgery

Surgery for liver tumors and cysts encompasses the removal or treatment of abnormal growths or fluid-filled sacs in the liver. Surgeons may employ techniques such as tumor resection or cyst drainage to address these conditions.

Liver Surgery

Liver surgery involves procedures related to the treatment of conditions affecting the liver. Surgical interventions may include liver resection, transplantation, or other targeted approaches to manage liver disorders.

Neuroendocrine Tumor Surgery

Surgery for neuroendocrine tumors focuses on the removal or treatment of tumors originating from hormone-producing cells. Depending on the location and nature of the tumors, surgical approaches may include resection or other targeted interventions.

Pancreas Cancer Surgery

Pancreas cancer surgery involves procedures to address malignant growths within the pancreas. Surgical interventions may include tumor resection, pancreaticoduodenectomy (Whipple procedure), or other approaches tailored to the specific type and location of the cancer.

Pancreas Tumor and Cyst Surgery

Surgery for pancreas tumors and cysts encompasses the removal or treatment of abnormal growths or fluid-filled sacs in the pancreas. Surgeons may employ techniques such as tumor resection or cyst drainage to address these conditions.

Pancreas Surgery

Pancreas surgery involves procedures related to the treatment of conditions affecting the pancreas. Surgical interventions may include tumor resection, pancreatitis management, or other targeted approaches to address pancreatic disorders.

Pancreatitis Surgery

Pancreatitis surgery involves procedures to manage inflammation of the pancreas. Surgical interventions may include drainage of fluid collections, necrosectomy, or other approaches to address severe cases of pancreatitis.

Retroperitoneal Sarcoma Surgery

Surgery for retroperitoneal sarcoma involves procedures to address malignant growths in the retroperitoneal space. Surgical interventions may include tumor resection or other targeted approaches to manage retroperitoneal sarcomas.

Splenectomy

Splenectomy is a surgical procedure involving the removal of the spleen. This intervention may be performed to address conditions such as splenic tumors, trauma, or certain blood disorders.

Whipple Procedure

The Whipple procedure, also known as pancreaticoduodenectomy, is a comprehensive operation primarily used to treat pancreatic cancer located in the head of the pancreas. This intricate surgery involves the removal of the head of the pancreas, the first part of the small intestine (duodenum), the gallbladder, and a portion of the bile duct.

In some instances, a minimally invasive Whipple procedure can be performed, which is a refined adaptation of the traditional Whipple surgery that utilizes laparoscopic or robotic techniques. This advanced approach involves smaller incisions, reducing trauma to surrounding tissues, and often results in a shorter hospital stay and faster recovery.

What Happens During HPB Surgery?

The procedures involved in HPB surgery vary significantly depending on the surgery performed. Each type of surgery within the HPB realm—whether focused on the liver, pancreas, bile duct, or gallbladder—entails a distinct set of procedures and techniques.

For instance, a Whipple procedure targeting pancreatic cancer involves intricate removal and reconstruction of organs, while a minimally invasive liver surgery necessitates smaller incisions and advanced technology for precise resections.

Similarly, a robotic hepatectomy or a vascular resection may require a different approach compared to traditional open surgeries. Therefore, the sequence of steps, the use of technology, and the overall surgical process will differ significantly based on the particular HPB surgery being performed.

Your HPG surgeon will guide you through the specifics of the procedure you are having performed, outline the steps involved, and address any concerns or questions you may have before embarking on the surgery.

Why You Should Use Caution When Selecting a Surgeon for HPB Surgery 

HPB surgeries stand out as some of the most challenging and complex procedures within general surgery; therefore, you should exercise caution when selecting a surgeon to perform an HPB procedure. 

While a general surgeon possesses a broad range of expertise, the intricate nature of HPB surgery emphasizes the need for specialization. This complex field demands practitioners with advanced training and experience due to its often challenging nature. 

Ensuring that your surgeon is skilled in HPB surgery is crucial for several reasons. HPB surgeries involve intricate and delicate procedures on vital organs, including the liver, pancreas, gallbladder, and bile ducts. These surgeries demand specialized techniques and a profound understanding of the unique challenges posed by conditions affecting these organs.

Surgeons specializing in HPB procedures dedicate significant time and expertise to master the nuances and complexities associated with these specific surgeries. Their specialized training ensures a deeper understanding of anatomical intricacies and potential complications during HPB procedures.

Moreover, a surgeon with a specific focus on HPB surgery is likely to stay abreast of the latest advancements and innovations in the field. Given the rapidly evolving landscape of medical techniques and technologies, a surgeon with specialized expertise can offer the most current and effective approaches to enhance the overall success and safety of the procedure.

Additionally, surgeons undertaking these procedures should ideally possess a profound understanding of the vascular system, particularly the intricate network of blood vessels, including veins, that connect the liver, pancreas, gallbladder, and bile ducts.

Choosing a surgeon with specialized knowledge in both HPB surgery and the vascular system ensures that the complexities of these vital organs are addressed with precision and expertise, significantly contributing to the success and safety of the procedure.

At The Surgical Clinic, we have surgical teams with vast knowledge of HPB conditions, HPB surgeries, and the vascular system, including vascular surgeries, offering comprehensive care for complex hepato-pancreato-biliary disorders.

How to Support a Loved One Having HPB Surgery 

Supporting a loved one through HPB surgery is a significant aspect of their journey. The level of support needed often depends on the invasiveness of the procedure. Despite the surgical intensity, offering comfort, understanding, and practical assistance is invaluable.

Being present and lending a listening ear provides substantial emotional support during this challenging time. Staying informed about their specific condition and the steps involved in their surgery enhances your ability to offer meaningful assistance.

For more invasive surgeries, practical support is crucial. Offering to accompany them to the surgery or coordinating transportation can be very helpful. Post-surgery, you can lighten their load by taking care of household tasks or running errands while they recover. 

Suppose you find yourself in the role of the primary caregiver. In that case, a deeper understanding of their condition and recovery might be required. 

You should be informed of all of their medications and know when to contact the doctor or seek emergency care. You should also be up-to-date on any follow-up appointments needed and help ensure they are scheduled.

Recovery following some HPB procedures can be long and daunting. Caring for a loved one following a major HPB surgery can be time-consuming, so make sure you are taking care of yourself, too. 

HPB Surgery, Vein Centers, and Vascular Procedure Centers in Middle Tennessee

As a leading surgical practice in Middle Tennessee– at The Surgical Clinic, we take pride in our expertise across various medical divisions and surgical disciplines, including the vascular system and realm of HPB surgery.

Our teams boast extensive expertise in performing HPB surgeries, demonstrating a deep understanding of conditions affecting the pancreas, liver, and biliary systems. Additionally, our vein surgery specialists bring a unique skill set to our practice, ensuring a well-rounded approach to HPB surgical care.

In striving for optimal outcomes, The Surgical Clinic employs cutting-edge techniques, including minimally invasive laparoscopic surgery, whenever suitable for HPB conditions. Laparoscopic procedures involve smaller incisions, resulting in reduced postoperative discomfort, shorter hospital stays, and quicker recovery periods compared to conventional open surgery.

Our board-certified and highly skilled HPB surgeons utilize advanced laparoscopic approaches in performing procedures such as cholecystectomy (gallbladder removal), liver resection, and pancreatic surgery with meticulous precision and compassion.

Patients who entrust The Surgical Clinic for HPB diagnosis and treatment receive the most advanced, patient-centric care available. Whether it pertains to treating liver and pancreatic cancers, intricate bile duct conditions, or other HPB disorders, our commitment to staying abreast of cutting-edge medical advancements ensures that patients benefit from the latest innovations in surgical care.

If you are navigating a condition related to the pancreas, liver, or biliary system and seek expert treatment, contact us for personalized and specialized care.